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The molecular clock appendix carefully discusses relevant technical challenges, theoretical models, and assumptions underlying the use of these techniques.
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A relaxed log-normal molecular clock was strongly favored over a strict clock rate (log10 BF>100), suggesting that mutation rates vary significantly among branches (Technical Appendix Table 4).
1) Molecular clock.
What is a Molecular Clock?
Variation in the molecular clock in primates.
The molecular clock as a metabolic rheostat.
Ayala, F. J. Molecular clock mirages.
J.H. Gillespie, "The molecular clock may be an episodic clock," PNAS 81 (1984): 8009-8013.
Weir, J. T. & Schluter, D. Calibrating the avian molecular clock.
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Correcting for purifying selection: an improved human mitochondrial molecular clock.
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