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Rapid input of sequences sets to TempEst for molecular clock analysis is assisted by the following expedient.
Molecular clock analysis suggests that human homologs of TryR i.e. Glutathione Reductase and Txnpx respectively are highly diverged in phylogenetic tree, thus, they serve as good candidates for chemotherapy of leishmaniasis.
To check for the closeness between human homologs of these proteins, we have carried the molecular clock analysis followed by molecular modeling of 3D structure of this protein, enabling us to design and test the novel drug like molecules.
We then plotted the rolling average, maximum and minimum values as a function of the number of trees in R. Due to computational limitations, we focused on ten maximum-likelihood trees that maximize topological diversity (as inferred on the basis of Robinson Foulds distances) as representative trees for molecular clock analysis.
Phylogeneticists often use a molecular clock analysis to determine the approximate timing of events on trees.
Accurate molecular clock analysis thus can be expected to give an earlier divergence time than the date of the earliest relevant fossil.
The molecular clock analysis of the children's HIV sequences convincingly showed that the medics could not have caused the disease cluster.
The result of a "non-synonymous" mutation from AGC to AGA would be a change in amino acid that potentially would be counted in a protein molecular clock analysis.
Molecular clock analysis suggests that slow lorises may have started evolving into distinct species about 10 mya.
Molecular clock analysis revealed that the exponential increase of the Ne was not due to an increased evolutionary or replication rate of HIV-1 in tissues with different histopathology.
The molecular clock analysis of the genetic diversity among the seven haploid major molecular lineages support the phylogenetic species concept, in which strains that form consistently the same monophyletic groups should be considered to be independent species [52], [53].
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