Purpose: Molecular classification of gliomas is a major challenge in the effort to improve therapeutic decisions.
Methylation of TSGs provided a molecular classification of NMI disease according to clinicopathological factors.
There is no established molecular classification of HCC, although preliminary proposals have already been published.
Over the last 5 years there has been a surge in interest in the molecular classification of colorectal cancer.
The first widely adopted molecular classification of rice groups was based on isozyme analysis (Glaszmann, 1987), in which six varietal groups were identified.
This is the first report on what's a proposed new molecular classification of breast cancer.
This demonstrated the relevance of our approach to the molecular classification of the main types of differentiated follicular thyroid pathology.
For instance, molecular classification of leukemia and lymphomas has tremendously enhanced our understanding of these diseases [2], [3], [4].
Finally, we were able to identify 220 non-redundant genes for the molecular classification of each of the 11 subcategories of follicular thyroid pathologies explored (Table 3).
Improving the molecular classification of tumours with respect to predictive or prognostic biomarkers is essential for appropriate stratified and personalised medical approaches.
Clinical applications of these DNA methylation based biomarkers range from early, possibly non-invasive cancer detection to more accurate molecular classification of confirmed breast cancers.
