Sentence examples for molecular classes to from inspiring English sources

Investigators then compared these three molecular classes to histologic classification of gliomas and to the biomarker classification of lower-grade glioma based on the status of IDH mutation and 1p/19q co-deletion.

To a first approximation, correlations of mobility with mass allow for qualitative identification of the molecular class to which a particular species belongs.

It is important to recognise that there is no standardised and uniformly accepted molecular assay to assign molecular class to breast cancer.

To assess the optimal Ki-67 LI cut-off in different molecular classes and to avoid data overfitting, each molecular class was randomly split into two subsets by using SPSS random sampling; one third of cases were used as a training set, and the remaining two thirds used as a validation (test) set.

This requires large molecules with good tolerability, and some biologically occurring molecular classes seem to be well suited in this respect.

Applying similar techniques, we were able to identify metabolites from numerous molecular classes that showed an ability to explain the variation in responsiveness to sodium nitrite.

To ensure the specificity of the antibody and to confirm the expression of KNPA2 in specific cell lines corresponding to molecular classes of BC, western blotting and reverse-phase protein microarray (RPPA) were performed as previously described (Mannsperger et al, 2010; Aleskandarany et al, 2014; Negm et al, 2014).

This indicates that a selected subset of representative molecules can be used to extend the model's predictive accuracy to new molecular classes.

From this one-dimensional approach evolved the current state of the art: expression profiling to uncover pathway regulation of gene expression and to define molecular classes on the basis of integration of the total signals experienced by the cancer cell.

Therefore, in the current study, we used a well-characterized series of operable invasive BC to assess the prognostic significance of Ki-67LI with regard to BC molecular classes compared with that provided by the routinely assessed MS and addressed some technical issues for use in routine practice in assessing tumor proliferation.

RPPA was used to evaluate the expression levels of KPNA2 in the cell lines corresponding to BC molecular classes used in this study.