Given the high incidence of HRV infections and ongoing exposure to other circulating (sero types, molecular characterisation is required to clearly document HRV persistence [27].
Differences in the functional morphology of all the spore stages within each species reflect the ecology of the ant host, and these are so pronounced that molecular characterisation is not required to separate them.
However, for this model to be effective for studying engraftment and therapy responses at the whole genome level, careful molecular characterisation is essential.
The molecular characterisation is an attempt to define homogeneous groups of patients for prognosis as well as for responsiveness to treatments (Almadori et al, 2005).
In addition to these pathological prognostic factors, which can only be identified post-surgically, molecular characterisation is expected to improve the identification of more aggressive or treatment-resistant tumours before therapy.
Taken all together, our data demonstrate that OSPC and USPC, two diseases where further molecular characterisation is needed to improve differential diagnosis and therapeutic strategies, can be readily discriminated solely by gene expression profiles.
Two new molecular characterisations were reported in 1991.
Twenty-five archived tumour samples from patients referred between 2009 and 2012 who were previously enrolled into a molecular characterisation study were analysed by the Sequenom OncoCarta v1.0 panel (Sequenom Inc).
