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The biochemical nature of the information transfer process implies that for molecular communication purposes, the development of molecular channel models should take into consideration diffusion phenomenon as well as the physical/biochemical kinetic possibilities of the process.
While this field is still in its infancy, it has increased our understanding of molecular channel regulation and holds great promise for future structure-function studies of these ion channels.
Moreover, open research challenges, such as extension of molecular channel models to multi-terminal cases, and developing a communication theory perspective to understand the physiology and to capture potential communication failures of intra-body biological systems, are provided.
In order to model a pathological molecular channel, one needs to specify the equations that determine the channel output, in terms of the channel inputs.
To calculate the capacity of the molecular channel, one needs the transition probability channel matrix M. Depending on which molecule is dominant in the pathological channel, one can use the matrices given in (12 - 16 12 - 16
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There were genes linked to transmitters that relay messages between neurons, and genes for molecular channels that move electrical signals up and down nerve cells.
We present the advanced software tool MOLE 2.0 designed to analyze molecular channels and pores.
Frequently, self-assembling methods were used to prepare the complex structure of these molecular channels.
We present an advanced software tool entitled MOLE 2.0, which has been designed to analyze molecular channels and pores.
Most people think only nerve cells have electrical pulses, but almost all cells have membranes perforated with molecular channels and pumps that let charged particles move in and out the essence of an electrical current.
The performance of all the considered software tools was compared on a set of thirteen diverse biomacromolecules containing several channels or pores: two RNAs, three membrane proteins, the photosystem II oxygen evolving center and seven representatives of enzymatic groups, which have all been targeted in research studies dealing with molecular channels (Figure 5).
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