Sentence examples for molecular changes were from inspiring English sources
Molecular changes were mapped in 23 striatal sectors mostly defined by their predominant cortical inputs in order to determine the functional domains affected.
Starting with the molecular scaffold of the DA2/β2 dual agonist sibenadet (Viozan™), a number of molecular changes were incorporated, which were designed to increase the potency and selectivity of the target molecule, and improve its pharmacokinetics.
Molecular changes were made at the PAT C(4 -position, while preserving N,N-dimethyl substitution at the 2-position as well as trans-stereochemistry, structural features previously shown to be optimal for 5-HT2 binding.
KRAS mutations or CNGs were significantly associated with increased ras GTPase activity, as measured by ELISA, and the two molecular changes were synergistic.
These molecular changes were mediated by iNOS/netrin/PKC signaling pathway downstream of Shh gene overexpression which combined with stem cell transplantation could be a promising strategy for the treatment of an infarcted heart.
Biochemical, histological, and molecular changes were investigated.
These molecular changes are similar, but not identical, to those produced by other psychostimulants.
The external stimuli, which can be combined in order to provoke these molecular changes, are numerous.
If further research supports Gimzewski and Rao's results, Barsky says, it will be important to find out what molecular changes are associated with cancer cells' structural changes.
A straight-line relationship indicates that the molecular changes are affecting the rates of the two reactions in related ways.
It remains to be seen whether the observed methylphenidate-induced molecular changes are driven by medial agranular cortical input (Vargo and Marshall, 1995, 1997) or other striatal inputs/mechanisms with a similar regional distribution.
