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These processes are therefore potential regulators of the molecular changes underlying permanent pain states.
This article reviews the molecular changes underlying pancreatic neoplasms, with a special focus on the genetic changes that characterize the histologic types of pancreatic neoplasms.
Extensive detailed description of these changes is beyond the scope of this review; instead, we aim to highlight some of the most significant processes and, where possible, the molecular changes underlying these and refer the reader to in-depth, subspecialist reviews of the individual components for further details.
The data presented here gain an insight into the molecular changes underlying the cold acclimation of trifoliate orange, and the results can be of reference for unraveling candidate genes that hold great potential for genetic engineering in an effort to create novel germplasms with enhanced cold stress tolerance.
Targeting transmembrane proteins - like E-cadherin - or increasing the levels of intracellular reactive oxygen species via enhanced activation of Rac1b are further mechanisms of MMP-induced EMT [38, 39]. Figure 1 Basic molecular changes underlying EMT.
Since the molecular changes underlying the pathological conditions are complex and heterogeneous, the ultimate solution to improve the accuracy of biomarkers appears to be the combination of biomarkers into a panel.
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An important question is which cellular and molecular changes underlie the behavioral recovery promoting effects of EE?
Over the past few years, the molecular genetic changes underlying cartilaginous and bone tumor development and progression have been increasingly elucidated.
As a result, only little is known about the molecular genetic changes underlying small bowel inflammation at the whole-genome level [ 6].
Understanding the molecular biological changes underlying the process of epileptogenesis is crucial to the development of newer, more effective treatment regimes.
Our finding that positive selection was especially prominent along the primate-origin lineage suggests that molecular-evolutionary changes underlying important features of complex social cognition were established well before separation of the human lineage.
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