Sentence examples for molecular changes seen from inspiring English sources
In addition to the molecular changes seen following Oct4 knockdown, we dissected the biological effects on the self-renewing hPSC SSEA3+ fraction.
While limited by the nature of in vitro cultured neural cells we have seen that molecular alterations induced by CMP may in-part mirror those molecular changes seen in brain tissues that have experienced long-term stress.
This could account for the coordination of the complex molecular changes seen in EMT.
The molecular changes seen in critically ill tissues and organs are either exaggerations of normal physiology or inappropriate expression of repair patterns.
In future, our work will be to continue validation of this model by evaluating the histological and molecular changes seen after tendon transection, and development of a chronic injury model.
The molecular changes seen in DCIS include mutations in the p53 gene [ 4], and gene amplification and overexpression at the protein level of the c-erbB-2 receptor tyrosine kinase [ 5].
This is supported by the similar distribution of stop codons, and underlying molecular changes (see below), as well as the retention of the aforementioned 17 and 48 bp regions in several other Oncorhynchus species and in S. salar.
To characterize at the molecular level the pathologic changes seen in thyr-IFNγ transgenic thyrocytes, we used long serial analysis of gene expression (Long SAGE) and compared gene expression in transgenic and wild type isolated thyrocytes.
Atrial supply-demand ischaemia has also been proposed as a potential trigger for atrial structural remodelling and has a molecular phenotype that resembles changes seen in hibernating ventricular myocardium.
Important inter-relationships between bone remodelling and angiogenesis are also now emerging, and so perturbations to angiogenic molecular pathways could contribute to the changes seen in OA bone.
Ultimately, understanding the molecular mechanisms that drive tissue-level changes seen in altered development should enable the design of improved cell-based assays that help transcend species differences.
