Sentence examples for molecular changes responsible from inspiring English sources
The molecular changes responsible for the biological activity of RA in melanoma are not well understood.
The knowledge of the molecular changes responsible for the production of such protected liver cell phenotypes is however still incomplete.
In summary, in this mouse model of breast cancer, the majority of the molecular changes responsible for tumorigenesis are already present in early premalignant lesions.
In order to identify underlying molecular changes responsible for the observed functional alteration in an age-altered systemic environment, we profiled the protein expression of yMSCs and aMSCs cultured in aSerum and ySerum, respectively.
These data suggest an alternative view that the early lesions are already equipped with the molecular changes responsible for tumorigenesis, despite the disparate histological characteristics between the early lesions and the invasive carcinoma.
To address these major challenges, we aimed to determine whether BC patient-derived xenograft (PDX -bearing mice could PDX -bearingnstant and renewable source of CTCs and Bmicecould a unique system to study the molecular changes resprovidee for tumor progression and metastases.
Having established that CDK9 inhibition efficiently sensitizes cancer cell lines to TRAIL-induced apoptosis, we next addressed which molecular changes are responsible for this effect.
DNA from the two surviving lineages was isolated, amplified, and sequenced (see Methods) in order to uncover which molecular changes were responsible for the isolate's ability to withstand long periods of elevated temperatures.
We are interested in understanding the molecular changes that are responsible for the evolution of this C4-characteristic PEPC expression pattern, and we are using the genus Flaveria (Asteraceae) as a model system.
First, the model usually takes as a starting point variation in morphology caused by anonymous, unknown mutations, and therefore does not inquire as to what molecular changes might have been responsible for the origins of variation.
In particular, molecular insights on epigenetic changes responsible for the occurrence of these phenotypes are missing.
