Sentence examples for molecular changes relevant from inspiring English sources

We here examine the molecular changes relevant to the defective AKT pathway that we have previously observed in highly differentiated CD8+ T cells.

Risk variants of TCF7L2 SNPs might be associated with several types of molecular changes relevant for T2D and our study addressed only one of these types, mRNA expression of alternative splicing forms.

It is, so far, incompletely known when the epileptogenic process begins, and which molecular changes are relevant to it.

Alternatively the study of peripheral tissues may offer some insight into the molecular basis of disease susceptibility and progression, but this approach still relies on brain tissue to benchmark relevant molecular changes against.

In addition, several novel molecular changes associated with clinically relevant endpoints have been demonstrated.

By performing combined bioinformatic analyses of the distinct large-scale data sets, we aimed to characterize aging-associated molecular changes and to identify relevant biological processes and regulatory mechanisms.

However, protection from a full-term pregnancy would also be consistent with cumulative dose effects of specific hormones throughout the pregnancy, or early hormonal events which require the subsequent action of others to induce the relevant molecular changes.

For example, Tim Whelan (McMaster University, Hamilton, Ontario, Canada) and Irene Andrulis (Lunenfeld Institute, Toronto, Ontario, Canada) outlined their group's conceptual framework for accelerating the discovery of clinically relevant molecular changes in breast cancer and rapidly translating these findings into novel treatment paradigms.

Tools based on FRET have been utilized to quantify several parameters of the cell material interface relevant to cell response, including molecular changes in matrix proteins induced by interactions both with surfaces and cells, the number of bonds between integrins and their adhesion ligands, and changes in the crosslink density of hydrogel synthetic extracellular matrix analogs.

Taken together, we have presented a novel 3D in vitro model that allows the study of cellular and molecular changes occurring in PCa cells and osteoblasts that are relevant to metastatic colonization of bone.

For ease of reference and to highlight the significance of the molecular changes observed, the molecular characterization results that appear most relevant are discussed in this section.