Sentence examples for molecular changes of from inspiring English sources

These data greatly contribute to understanding the molecular changes of LSCs and developing novel therapies for eradicating LSCs and even achieving curable effect of CML.

However, there is no clear data demonstrating whether such molecular changes of EGFR per se can affect the clinical outcome of early stage cancer after surgical resection.

The difference of radiopharmaceutical structure between 11C-4DST and 18F-FLT (Figure 1A,B) is small; however, it has been recognized that small molecular changes of the chemical structure sometimes make greater difference in the pharmacokinetics of PET tracers.

The molecular changes of LNCaP cells after co-culturing with TEBs suggest that osteoblasts exert a paracrine effect that may promote osteomimicry and modulate the expression of androgen-responsive genes in LNCaP cells.

RPPA proteomics technology was used to investigate the molecular changes of the signaling status in vivo that would influence the [18F] FDG uptake in NCI-H2122 tupons upon treatment since it permits multiplex, highly sensitive, and reproducible quantitative analysis of protein expression and phosphorylation levels.

To explore whether neuronal axons are affected under infrasonic insults, we exposed cultured hippocampal neurons to infrasound with a frequency of 16 Hz and a pressure level of 130 dB for 1 h, and examined the morphological and molecular changes of neuronal axons by immunocytochemistry and Western blotting, respectively.

NF-κB1, ERK, and STAT3 are positive regulators of this cell-to-cell communication mediated molecular change of IL-10 induction.

The histological and molecular change of the gland during pregnancy can be appreciated by the increase in cross-section area and total DNA, as well as the breadth of pathways affected (Fig. 8).

Molecular detection strategies from airway specimens are challenging because of the relatively difficult access, paucity of tissue and lack of molecular changes predictive of cancer.

The third category of molecular changes consists of variation in the levels of gene expression between species and in the mechanisms regulating gene expression [ 8, 10].

An important new paradigm in biomarker discovery research is to consider entire sets of molecular changes, instead of single parameters, that correlate with a particular disease [ 43].