Sentence examples for molecular changes detected from inspiring English sources

In the resulting model system for HPV-mediated multistep transformation of human keratinocytes (Figure 4), we demonstrated that HPV16 induces pre-neoplastic alterations that parallel many of the molecular changes detected in cervical cancer [78], therefore validating the model system as a suitable context in which to study molecular mechanisms of HPV-mediated immortalization and tumor progression.

The molecular changes detected suggest that cellular transformation and acquisition of aggressive phenotype involves "re-programming" of cellular systems, especially in processes associated with carbohydrate, amino acid and lipid metabolism.

The molecular changes detected could potentially act as biomarkers to assess fenitrothion toxicity in field-sampled chronically exposed roach.

Considerable progress has been made in explaining these early molecular changes by detecting alterations in the biochemical composition of the cartilage using MRI biomarkers such as T1ρ, T2, dGEMRIC, and sodium MRI (Choi and Gold 2011).

For example, the metabolic changes detected in blood and urine can reflect the molecular phenotypic response of an individual to an environmental insult.

Molecular changes that are commonly detected in margins as well as the corresponding tumor could indicate that pre-malignant or malignant clones were able to migrate to the surrounding tissue, giving rise to a primary tumor recurrence [ 35].

Measurement of ZP is an easy and relatively quick way to detect molecular changes that have occurred on the membrane surface of live cells.

Molecular MRI of liver fibrosis has been used to directly detect molecular changes in the ECM and HSCs.

Hence, some tests may be capable of detecting molecular changes associated with tumor recurrence earlier than cystoscopy [ 8, 9].

Another possibility is that EGIR-based genomic assay can detect molecular changes prior to the development of morphological abnormalities in melanoma cells.

In the acute protocol, mice were injected with 3 mg/kg of l-DOPA and 20 min after they were perfused to detect molecular changes without scoring AIMs.