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Such approaches allow cross validation and correlation of findings with underlying molecular changes contributing to treatment outcome.
This review will focus on the molecular changes contributing to the pathogenesis of HNSCC and their clinical implications in designing new therapeutic strategies.
At disease progression, biopsy of metastatic sites will be performed to elucidate the molecular changes contributing to treatment resistance, which may help to determine the next treatment choices.
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Recent work has established that DNA methylation is altered in epilepsy and that these molecular changes contribute to persistent gene regulation in the hippocampus.
This study attempts to reveal the molecular and morphological changes contributing to congenital heart defects in embryos of diabetic pregnancy.
The presence of molecular changes that contribute to enhanced proliferation and growth were reviewed previously in the sections discussing biological activities contributing to early age of onset and to more advanced stage at presentation.
By identifying the cascade of molecular changes that contribute to the development of epilepsy we hope to be able to design therapeutics for preventing epilepsy.
Status epilepticus (SE) induces a cascade of molecular changes that contribute to the development of epilepsy.
Identifying such molecular changes may contribute to improved clinical management and outcome prediction of newly diagnosed neuroblastomas.
Therefore, it is important to identify the molecular changes that contribute to the malignant progression of this disease.
Elucidation of the cellular and molecular changes that contribute to disease progression requires tissue samples from disease sites.
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CEO of Professional Science Editing for Scientists @ prosciediting.com