This ranges from new insightsinto the molecular changes associated with pathogenesis.
Co-administration of epigallocatechin-3-gallate (25 100 mg/kg) significantly and dose-dependently prevented functional, biochemical and molecular changes associated with alcoholic neuropathy.
To further define the molecular changes associated with PrPSc accumulation in cultured cells, the transcriptional profile of PrPSc-accumulating primary ovine microglia was compared to the profile of PrPSc-lacking microglia using the Affymetrix Bovine Genome Array.
In order to identify additional molecular changes associated with the presence of β-galactosidase mutations, the expression of canine lysosomal multienzyme complex components in GLB1+/+, GLB1+/− and GLB1−/− fibroblasts was investigated by quantitative RT-PCR, Western blot and enzymatic assays.
To define the molecular changes associated with this process, expression profiles were compared in emodin-treated hepatoma cells by cDNA microarray hybridization, quantitative RT-PCRs, and Western blot analysis.
Here we have characterized the molecular changes associated with TMC generation.
Postmortem human brains are critical for examining molecular changes associated with the pathophysiology of neuropsychiatric diseases.
Herein we are able to analyze structural, functional and molecular changes associated with acute MI.
These results suggest that podocalyxin may contribute to the regulation of the molecular changes associated with EMT.
Primary cultures from RCC cancers are useful tools to study the biochemical and molecular changes associated with the neoplastic status.
Indeed, we have recently shown that CNTF-activated astrocytes display marked phenotypic and molecular changes associated with an improved handling of extracellular glutamate in the rat striatum [12].
