Fortunately, the increased understanding of the molecular basis and heterogeneity of the disease has fostered the development of novel agents.
Further, constituents such as bitumen or heavy oil are ill-defined on a molecular basis and their critical and other properties are not accessible experimentally.
In this review, we will discuss the molecular basis and implementation for some of these novel treatments with particular emphasis on BRAF and BRAF inhibitors.
The genes, molecular basis and functional genomics of PHA synthesis by H. mediterranei and related archaea were studied by Xiang's research group (Liu et al. [2011] and relevant references therein).
By integrating the information obtained with these complementary approaches the field is currently obtaining an unprecedented level of understanding of the biology, molecular basis, and therapeutic vulnerabilities of metastasis.
This work was done to establish the molecular basis and regulation of the formation pattern of cadherin/β-catenin-mediated adherens junctions, using an animal model of unknown gene sequence, the toad Rhinella arenarum.
The molecular basis and the pathophysiology of MOH are still largely unknown, although it has been hypothesized that this condition could be mediated by cognitive impulsivity, and shares some dysfunction mechanisms with drug addiction [4], probably involving factors beyond the pain alone, such as certain behaviors and psychologic states [5].
The new strategy will benefit the further study of the molecular basis and evolution of transcriptional regulatory networks underlying the phenotypic variation between rice subspecies japonica and indica.
The identification of critical genes involved in its pathogenesis will be central to advances in our understanding of its molecular basis, and the development of improved therapeutic approaches.
These data have provided new insights into the molecular basis and significance of biofilm formation by S. pneumoniae and by pathogenic bacteria in general.
Our study will assist in the search for important marker genes for rice phenotypic variation between japonica and indica subspecies, and will also yield new insight into the molecular basis and evolution of transcriptional regulatory networks underlying phenotypic variation.
