It was found that the CMC and corresponding molecular areas values ranged from 0.98 to 4.17 g L−1 and 166 to 775 Å2, respectively.
Polar molecular surface area values indicate fenofibrate and iPr clofibrate are less able to act as acceptors of hydrogen bonds than their corresponding acid derivatives.
Surface area calculations show that dynamic polar molecular surface area values of the iPr esters of the fibrates are lower than those of their acids, implying that the fibrates have better membrane permeability and a higher absorbability and hence are better prodrugs when these agents need to be orally administered.
The synthesized array, containing 56 previously unknown structures, was shown to possess attractive molecular weights, lipophilicities, and polar surface area values for drug-like space.
Surface active properties of analyzed chlorides were described by the following parameters: CMC: critical micelle concentration (mol/L), γ CMC: value of surface tension at critical micelle concentration (mN/m), Γ × 10 (G ): value of surface excess (mol/m), A × 10−20: molecular area of a single particle (m), Δ G ads: free energy of adsorption of molecule (kJ/mol).
CMC: critical micelle concentration (mol/L), γCMC: value of surface tension at critical micelle concentration (mN/m), Γ × 10 (G): value of surface excess (mol/m), A × 10−20: molecular area of a single particle (m), Δ Gads: free energy of adsorption of molecule (kJ/mol).
At t = 0.5 min, enzymatic denaturation of the collagen structure was fairly moderate and the calculated molecular area (see Supporting File S1 and Supporting Figure S7 for details) exhibited an average value of 4.8±2.2×104 Å2.
These aerogels obtained by supercritical carbon dioxide extraction of thermoreversible gels of high molecular weight PPO present an apparent porosity typically in the range 70%–95% and high surface area values up to 750 m2/g.
The mean molecular area declined as the surface pressure increased.
Total Partially Positive Surface Area Total molecular area that has a partially positive charge.
