Sentence examples for molecular anomaly from inspiring English sources
As long as researchers understand the crucial molecular abnormality in a cancer, design a drug to fix that problem, and use it in only in patients who have that molecular anomaly, then such targeted therapies can be effective.The need for combinationsIn general, the academic community and pharmaceutical companies agree with this assessment.
3, 43 The association of 22q11.2DS with schizophrenia followed soon after the discovery in the early 1990s that the 22q11.2 deletion was the underlying molecular anomaly unifying several, seemingly distinct, clinical syndromes first described in the 1960s and 1970s.
Other new products, once barely imaginable, include: In Milan, Italy, haberdashery futurists testing chemical compounds in pursuit of a fireproof tuxedo stumble onto and right through a molecular anomaly.
One such promising strategy is gene therapy to target underlying molecular anomalies in the dysfunctional cardiomyocyte.
Enhanced efforts to define subsets of patients with prostate cancer based on their molecular anomalies, and match them with cognate therapies, warrant investigation.
HRM could be more cost effective than direct sequencing for identification of molecular anomalies in ADPKD.
Recent studies by Wu et al. and Furukawa et al. added important information about the molecular anomalies of IPMN [ 70, 71].
This approach is shifting the traditional organ-based classification of cancer towards a new molecular taxonomy, and creating opportunities to apply therapeutics for the treatment of cancers originating in other organs that harbour similar molecular anomalies.
Unlike most clinical descriptions of patients presenting SHANK3 deletions and Phelan McDermid syndrome, our patients present a somewhat different phenotype which might be linked to the size and location of the molecular anomalies [ 3, 13].
The patient genotype of the BCL2−938C > A polymorphism was not correlated with patient outcome or with clinical risk markers, including prednisone response or identified molecular genetic anomalies.
No difference concerning OS or EFS between good or poor prednisone responders or between the identified molecular genetic anomalies was detected (Data not shown).
