Sentence examples for molecular alternation from inspiring English sources

The sophisticated molecular alternation which occurs during hepatocarcinogenesis provides a long-lasting challenge for researchers.

These JAK2 and MPL mutations are also considered as the driver molecular alternation of the disease because of the resulting constitutive activation of JAK-STAT pathway.

These results implied a possible role of the loss of PTEN and the following activation of the PI3K AKT mTOR pathway in the development of the present rat model of MTOE and a shared molecular alternation of the present rat model of MTOE with human low-grade endometrioid adenocarcinoma.

Despite recent progress in the identification of genetic and molecular alternations in colorectal carcinoma, the precise molecular pathogenesis remains unclear.

Genetic and molecular alternations that are likely to cause tumor formation are often organized into complex biological networks.

Using established EBV-negative NPC cell lines and advanced molecular biology techniques, our understanding of molecular alternations in these cells has been tremendously improved [ 40– 40].

Several molecular alternations in RAS gene have been identified such as minisatellites and mutations, however, research on the single nucleotide polymorphism in RAS gene was rare [ 18- 20].

In the past years, there has been an explosion in our understanding of the molecular alternations occurring in HCC, through which a series of molecular biomarkers were identified in terms of both their prognostic significances and potentials as therapeutic targets.

The short term effects of endotracheal suctioning are clear (i.e., desaturation and loss of lung volume), but long term and repetitive effects, especially lung injury or molecular alternations, are not clear.

This study was aimed to generate a mouse model of seipinopathy and to elucidate the cellular and molecular alternations in the CNS as a result of N88S/S90L mutant Seipin expression, with the view that this would lead to better understanding of the pathological changes in seipinopathy.

As 37LRP/67LR belongs to non-integrin adhesion molecular family, the alternation in the mechanisms of invasion or metastasis in GC need to be characterized.