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Differences in the molecular alterations underlying the development of uterine sarcomas and adenocarcinomas are significant.
However, prognostic stratification and treatment decision for the intermediate risk category, that mostly comprises AML patients with normal cytogenetics (CN-AML), has been difficult due to the clinical heterogeneity and scarce knowledge of the molecular alterations underlying this large AML subgroup.
Furthermore, network-based analyses can be used to identify biomarkers [6], to predict tumor progression [7], or to reveal the molecular alterations underlying disease [8].
Next, to estimate molecular alterations underlying tumor progression to malignancy, data sets representing whole tissue sections from colonic neoplasms were decomposed into SVD modes (Figure S2) and analyzed by pair-wise comparisons (Table S5).
Currently, the molecular alterations underlying the majority of these mutations are elusive.
However, the molecular alterations underlying glioma patients' response to PDGFRA antagonists are unknown.
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54 The exact sequence of molecular alteration underlying gallbladder cancer pathogenesis remains unclear.
Several experimental models of posttraumatic epilepsy are currently in use that may facilitate discovery of molecular and pathophysiological alterations underlying the process of epileptogenesis.
In this study, we used C. elegans male mating behavior to study the molecular and physiological alterations underlying the behavioral decline that occur during early aging.
Molecular oncology testing (MOT) to detect genomic alterations underlying cancer holds promise for improved cancer care.
During recent years, genetic and molecular alterations that underlie this disease have been identified and advanced our basic knowledge about gliomagenesis.
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