Sentence examples for molecular alterations occurring from inspiring English sources
A prerequisite for this development was the comprehensive characterization of molecular alterations occurring in human hepatocellular carcinoma (HCC).
We interrogated the molecular alterations occurring in breast cancer using proposed EMT markers such as E-cadherin, vimentin, epidermal growth factor receptor (EGFR), platelet-derived growth factor (PDGF) D, and nuclear factor κB (NF-κB) to decipher their roles in the EMT and breast cancer progression.
The latter finding was most evident in non-tumor tissue, likely reflecting the widely recognized field-cancerization effect by smoking,[22] while in the tumor tissue, smoking-related genes' effects on survival may be masked by extensive molecular alterations occurring during tumorigenesis.
Aim of this study was to characterise genetic and epigenetic molecular alterations occurring in primary advanced M+ and M− CRCs.
A number of molecular alterations occurring in MPM have been reported, providing deeper insights into its biology and leading to the identification of novel druggable targets (Zucali et al, 2011a, 2011b).
There has been an explosion in our understanding of the pathophysiology and molecular alterations occurring in HCC and a series of molecular biomarkers that have potential prognostic significance and may be therapeutic targets have been identified over the past decades.
As a whole, this gene signature suggests a series of molecular alterations occur in aggressive melanomas that promote melanoma cell growth, survival and apoptotic resistance which contribute to the unresponsiveness of melanomas to traditional chemotherapeutic agents [51].
Various molecular alterations occur in preneoplastic nodules and escalate in HCC [ 4].
Various molecular alterations occur in precancerous lesions and are escalated in oesophageal carcinoma (EC) (Lin et al, 2013).
Molecular alterations occur frequently in T-ALL and the potential impact of those abnormalities on outcome is still controversial.
The obtained data demonstrated that quite complicated molecular alterations occurred in the studied region of spring polyploid species.
