Sentence examples for molecular alterations mediated from inspiring English sources

In the present study, we identified novel molecular alterations mediated by Hp involved in early and late cardiac repair responses after left coronary artery ligation in Hp−/− and wild-type (WT) mice.

With the development of cancer therapies that specifically target molecular alterations that mediate cancer progression, genotyping of patients with advanced CRC has become a component of routine clinical practice.

Molecular alterations in the prostate cancer proteome mediate the functional and phenotypic transformation from clinically localised to metastatic cancer, a transition that drives patient's mortality and challenges therapeutic intervention.

(3) One of the most common molecular alterations in HNSCC is the abrogation of p53 function, which is mediated by mutations of its gene, p53, loss of heterozygosity of p53, or interaction with HPV oncoprotein E6. (4– 6) Tobacco smoking increases the frequency of p53 mutations in a dose-dependent manner, 7) whereas E6 binds and degrades p53.

Although it is clear that these conditions are mediated by specific neurobiological processes [2], [3], the precise molecular alterations and the brain circuits involved in suicide and major depression remain largely unknown.

Molecular alterations also serve as convenient "markers" of disease.

Cancer evolves through the emergence and selection of molecular alterations.

Recent reports on genetic and molecular alterations in CNO patients indicate complex and variable immune pathology.

These morphological alterations in the cribriform PIN/CIS lesions were also accompanied by molecular alterations.

Therefore, molecular alterations that influence CDR entropy may also affect affinity.

In addition, molecular alterations also may have the potential to affect cell survival after analogs treatment.