Sentence examples for molecular alterations consistent from inspiring English sources
Further analyses showed that this cell line exhibit phenotypic and molecular alterations consistent with EMT.
Further evidence was provided by xenografts in nude mice; molecular alterations consistent with EMT were detected in tumors on day 7 after chemotherapy.
Bearing in mind that changes of DNA methylation pattern were observed in genomic DNA from lungs of the transgenic animals rather than tumor cells, our results suggest that overexpression of ΔDNMT3B4-del is able to disturb the normal DNA methylation pattern to facilitate early stage molecular alterations and morphologic changes consistent with initiation of tumorigenesis.
This study suggests that the loss of PG immunoreactivity at the intercalated disk is the result of complex molecular alterations in the myocardium, which is consistent with the fact that the immunoreactive signal for PG is reduced in the vast majority of ARVC cases, even in those where no mutation in a known ARVC disease gene could be identified.
In this study, we show that SPC-A-1sci cells display morphologic changes consistent with EMT, and that some molecular alterations have taken place in these cells, such as loss of E-cadheirn from the cell membrane of SPC-A-1sci cells.
Molecular alterations also serve as convenient "markers" of disease.
He was a noted researcher whose work centered on identifying and characterizing the clinically relevant molecular alterations in human cancers and the changes in gene expression that contribute to the development of cancer.
Cancer evolves through the emergence and selection of molecular alterations.
Recent reports on genetic and molecular alterations in CNO patients indicate complex and variable immune pathology.
Open image in new window Figure 1 Multiple cancer hallmarks and the underlying molecular alterations in the progression of HCC.
Fig. 1 Molecular alterations cause metabolic switching in cancer cells and severe metabolic changes in the tumor microenvironment.
