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Therefore, further studies are needed to uncover the potential hidden molecular alterations common to both diseases.
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These epithelial and stromal defects persist later, creating an indeterminate epithelium with molecular alterations in the common channel.
This manuscript integrates genetic data from publicly available array comparative genome hybridization (aCGH) and next-generation sequencing genetics databases to identify the most common molecular alterations in HNSCC.
Targeting the constitutive activation of YAP/TAZ for therapeutic treatment may address a diverse spectrum of different molecular alterations funneling into a common transcriptional activator.
Alterations in DNA methylation are the most common molecular alterations in human malignancies.
DNA methylation changes have been recognized as one of the most common molecular alterations in human tumors, including CRC.
Epigenetic defects have turned out to be one of the most common molecular alterations in human neoplasia.
Changes in the DNA methylation status are one of the most common molecular alterations in human neoplasia.
Aberrant DNA methylation has been recognized as one of the most common molecular alterations in human neoplasia.
Epigenetic alterations, especially aberrant DNA methylation, are recognized as common molecular alterations in a variety of tumors and also occur during the development of tumors.
In addition, novel methods of detecting common molecular alterations in colorectal cancer cells, such as methylation changes in fecal DNA [ 4], are being evaluated.
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