Sentence examples for molecular alterations between from inspiring English sources

The KEGG signaling pathways derived from both gene expression measurements and both lists of probe sets (selected by SVD and pair-wise comparisons) seem to represent the most reliable findings on molecular alterations between normal and neoplastic colon tissue (Table 3).

Despite this assumption, differences in specific molecular alterations between primary tumours and metastases were not consistently reported (Vignot et al, 2012).

It will be important to understand why there is such poor agreement regarding specific molecular alterations between studies and why molecular signatures provide only modest improvements over conventional prognostic and predictive factors.

For a better understanding of the differences in molecular alterations between primary and metastatic tumours, we examined the KRAS, BRAF, and PIK3CA mutational status and the MSI status in 26 primary tumours, 26 matched liver metastases, and 6 LN metastases.

Emerging reports of shared molecular alterations between LCIS and adjacent invasive lesions in parallel with genomic evidence that LCIS may be one of several early identifiable lesions in the pathogenesis of low-grade cancer have re-opened the debate regarding the true significance of LCIS and its precursor potential.

The use of laser microdissection [LCM (laser capture microdissection)] to capture defined cell populations from a complex solid tissue has been crucial in the assessment of molecular alterations between ductal epithelial cells and cells that have extravasated from the mammary duct.

On the basis of their pathological features and of the fact that a large proportion of them demonstrate RET-PTC translocations, these cancers are considered as similar to classical sporadic papillary carcinomas, although molecular alterations differ between both tumours.

Recently, Niskakoski and colleagues [ 41] investigated 107 ovarian tumors (20 from LS and 87 sporadic), in order to gain insights into ovarian tumorigenesis and to analyze molecular alterations that differ between LS and sporadic ovarian cancer.

There was no association between molecular alterations in the PI3K pathway and efficacy.

In this study, we present genetic and molecular alterations and key associations between WWOX, RUNX2 and VEGFA expression in human OS.

Molecular alterations and the interaction between these cells play a key role in axonal outgrowth and guidance into the target tissue [ 5, 7].