Sentence examples for molecular alteration in from inspiring English sources

Therefore, the congenital hypothyroidism model disturbs ERK 1/2 and p38MAPK phosphorylation pathways causing an important molecular alteration in the hippocampus.

Among the 106 non-responsive patients, 74 (70%) had tumors with at least one molecular alteration in the four markers.

Epigenetic changes, in particular DNA methylation, are recognized as one of the most common forms of molecular alteration in human cancer [1], [2].

Even though we could not detect any major modifications in myelin structure in Ins2Akita/+ PNS (Fig. 3A C), subtle molecular alteration in myelin gene expression could provide an early marker of later stage irreversible pathological changes.

However, whether this methylation-driven gene silencing mechanism represents a potential field effect due to an unidentified molecular alteration in normal mucosa or the expression of pre-existing multiple hyperplastic polyps from which CRC arises through the serrated pathway [38], as it has been recently suggested [32], remains unknown.

DNA methylation is an early and frequent molecular alteration in cervical Carcinogenesis.

He was a noted researcher whose work centered on identifying and characterizing the clinically relevant molecular alterations in human cancers and the changes in gene expression that contribute to the development of cancer.

Recent reports on genetic and molecular alterations in CNO patients indicate complex and variable immune pathology.

Open image in new window Figure 1 Multiple cancer hallmarks and the underlying molecular alterations in the progression of HCC.

Multiple cancer hallmarks and the underlying molecular alterations in the progression of HCC are summarized in Fig. 1.

Molecular alterations in downstream effectors of epidermal growth factor receptor may confer resistance to epidermal growth factor receptor inhibitors.