Sentence examples for molecular abnormalities to from inspiring English sources

This review also links molecular abnormalities to cellular pathology as much a possible and provides a framework of temporal relationships.

Recent data have revealed that epigenetic alterations, including DNA methylation and chromatin structure changes, are among the earliest molecular abnormalities to occur during tumorigenesis.

Likewise, epigenetic alterations, including DNA methylation and chromatin structure changes, are among the earliest molecular abnormalities to occur during tumorigenesis.

In the current study we investigated the capacity of molecular abnormalities to increase the accuracy of disease risk stratification above that afforded by clinical staging alone.

In summary, the present study found that the combination of hyperestrogenemia with type II diabetes in a rat EMs model can induce MTOE, which showed similar morphological changes and molecular abnormalities to human disease.

Clear-cell cancers, in contrast, show similarities to renal cancers (Zorn et al, 2005), whereas endometrioid cancers show similar molecular abnormalities to endometriosis (Wiegand et al, 2010), and mucinous ovarian cancers may represent metastases from primary tumours in the gastrointestinal tract (Lee and Young, 2003).

The underlying genetic and molecular abnormalities related to PFIC have led to the identification of three subtypes and the description of several mutations in hepatocellular transport system genes involved in bile formation.

This article reports that children with asthma who are passively exposed to tobacco smoke had the same molecular abnormalities leading to in vitro steroid resistance as do adults who actively smoke.

The goal of this study was to provide a detailed evaluation of lung cancer tumor markers indicative of molecular abnormalities and to assess their diagnostic utility in non-small cell lung cancer (NSCLC) patients.

In cancer, an array of molecular abnormalities leading to the modulations in expression of key proteins important in the cellular signaling pathways and cell proliferation has been identified.

Despite the progress in targeting particular molecular abnormalities specific to different cancers (targeted therapy), chemo- and radiotherapies are still the most effective of all anticancer modalities.