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We would like to speculate that this phenomenon may relate to some of the molecular abnormalities seen in slowly developing disorders of the brain, such as schizophrenia, which is not associated with gross neurological changes as well.
If, however, these protein abnormalities are not associated with LM deficits, an alternate explanation is that one or more trisomic proteins directly or indirectly act to protect the Dp10 from the deleterious effects of overexpression of other trisomic genes, i.e., the constellation of molecular abnormalities seen here is a sum of deleterious effects and neutralizing, compensatory responses.
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This suggests that cysteinyl leukotrienes may play a role in the abnormalities seen in BPD.
Changes in the nigrostriatal system may be involved with the motor abnormalities seen in aging.
Renal osteodystrophy encompasses the bone histologic abnormalities seen in patients with chronic kidney disease (CKD).
These changes are further responsible for the various structural and functional abnormalities seen in diabetic retinopathy.
In our previous study, we proposed a classification system for radiological abnormalities seen in hemodialysis-related hip lesions.
These experiments provide evidence that Tat protein expression is sufficient to mediate cognitive abnormalities seen in HIV-infected individuals.
Notably 73.56% of study CXRs were abnormal and lung parenchyma abnormalities were the biggest abnormality seen by the radiologists.
So, just as the nanodiamond material searches through the body to find molecular abnormalities, it also gets rid of them at that very moment.
Other histologic subtypes have different underlying molecular abnormalities, although responses to VEGF and mTOR targeting therapies have been seen in subsets of non-clear cell tumors as well.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com