Sentence examples for molecular abnormalities at from inspiring English sources

The brainchild of Dr. Ambika Bumb, who holds a PhD in biomedical engineering from Oxford, these nanodiamonds can detect molecular abnormalities at a much earlier stage, essentially stopping cancer from spreading any further.

Among the 35 patients with TP53 mutations, 13 (37.1%) showed additional molecular abnormalities at diagnosis (Tables 1 and 4).

To gain further insight into mechanisms and pathways involved, our study focused on the molecular abnormalities at 2 4 weeks of age [ 3, 4].

The success of breast cancer treatment relies on the ability to detect the disease and correct molecular abnormalities at an early stage of disease development.

These results confirmed that even morphologically normal, high-grade oocytes in the in vitro fertilization programme may express some molecular abnormalities at the gene expression level, especially those related to the failure of MII oocyte activation.

In the comprehensive analyses of the 17 gene mutations in 500 patients, we found that 13 (37.1%) of 35 patients with TP53 mutations showed additional molecular abnormalities at diagnosis, including NRAS, PTPN11, CEBPA, RUNX1, ASXL1 and TET2 mutations that occurred in 2 patients each.

These additional molecular abnormalities were at times evident long before treatment including, in one case, 17 months prior to starting targeted therapy (case #8).

Another implication from these interesting findings is that the increased risk of malignancy associated with SDHB would not be a direct result of SDHB protein loss but relate to other molecular abnormalities perhaps occurring at the transcriptional level.

Of interest, in each case, despite the complexity of aberrations revealed by NGS, many of the molecular abnormalities can be shown to converge, at least in part, on the PI3K/AKT/mTOR axis, perhaps accounting for the responses.

So, just as the nanodiamond material searches through the body to find molecular abnormalities, it also gets rid of them at that very moment.

AML pathogenesis is attributed to several recurrent chromosomal abnormalities in nearly half of the AML cases while the rest of the AML cases show at least one or more molecular abnormalities.