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Residential dampness and mold are associated with substantial and statistically significant increases in both respiratory infections and bronchitis.
The results of these meta-analyses indicate that building dampness and mold are associated with moderate but statistically significant increases in respiratory infections and bronchitis.
Indoor dampness and mold are associated with upper respiratory tract symptoms, cough, wheeze, and asthma symptoms in sensitized asthmatic persons (IOM 2004).
Fisk et al. (2007) concluded that "building dampness and mold are associated with approximately 30 50% increases in a variety of respiratory and asthma-related health outcomes".
The results of the present quantitative meta-analyses are consistent with the WHO findings for respiratory infections, but imply more strongly that dampness and mold are associated with bronchitis.
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"We do know for a fact that mold is associated with cognitive impairment in some people," says Dr. Wayne Gordon, a neuropsychologist and professor of rehabilitation medicine at the Mount Sinai School of Medicine in Manhattan, and one of a small but growing group of scientists who have come to specialize in the health effects of mycotoxins.
Dampness or mold was associated consistently with bronchitis [Supplemental Material, Table A2.7 (doi:10.1289/ehp.1002410)], with 96% of ORs > 1.0.
Fisk et al. (2010) estimated that residential dampness or mold is associated with 8 20% of U.S. respiratory infections.
Dampness or mold was associated consistently with eczema [Supplemental Material, Table A2.12 (doi:10.1289/ehp.1002410)], with 89% of ORs > 1.0 (range 0.2 to 2.9).
Dampness or mold was associated consistently with allergic rhinitis (92% of findings, all in children), with ORs ranging from 0.7 to 3.5 [Supplemental Material, Table A2.14 (doi:10.1289/ehp.1002410)].
For example, one NCS hypothesis holds that exposure to several indoor and outdoor air pollutants, including particulate matter (PM), ozone, and certain volatile organic compounds (VOCs), and bioaerosols (including allergens, endotoxin, and mold) is associated with an increased incidence of asthma in children.
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