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We established decision rules for determining solubility classes using measured log solubility in molar units (MLogSM) or measured solubility (MSol) in mg/ml units.
Tests will be precisely characterized and calibrated in SI units using six International Reference Reagents (IRR) for hCG and variants, and the Fifth International Standard for hCG 07/364, making it possible to report clinical results in molar units.
When the value (1/3 v2 is substituted for vz2 in the expression for pressure, the following equation is obtained: To rewrite this in molar units, N is set equal to nN0 i.e., the product of the number of moles n and Avogadro's number N0 to give where M = N0m is the molecular weight of the gas and v is the volume per mole (V/n).
Using an ATP standard curve, sample RLUs were converted to molar units of ATP and a dose response curve was generated.
For pteridine, the solubility of log S = 0.02 was measured by CheqSol and reported in Palmer et al. [37] Two reports from Albert et al. in the 1950's of solubility of "one part pteridine with 7.2 or 7 parts water" have been translated by Yalkowsky et al. into molar units to give log S = − 0.02 and − 0.03, respectively, and hence barely differ from the CheqSol result [73 75].
C∶N, C∶P, and N∶P ratios were calculated in molar units.
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In some cases it is unclear what the molar unit is.
Pharmacokinetics and pharmacodynamic studies comparing the intravenous administration of glulisine and regular insulin have shown a similar onset of action within 20 min, a similar distribution and elimination profile, and equivalent glucose utilization and disposal on a molar, unit-per-unit basis (16, 17).
Total amount of secreted IL-2 was calculated as the integral of [IL-2](t) over time t, using the method of trapezoidal approximation, normalized over the duration of the experiment and reported in the molar unit M. Tfinal ranges from 80 to 150 hr depending on the experimental conditions.
Concentrations of the PFAs were transformed to log-molar units, and it was seen that after this transformation the measured exposures approximately follow a normal distribution.
For the particular case of data used in the study on PFAs, the surrogate variables are measured concentrations of PFOA, PFOS, and PFHxS, which correspond to the exposures to the compounds reported on a continuous scale in log-molar units.
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