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Exact(9)
Several compounds with single-digit or even sub-nanomolar potency, suitable for further elaboration of the nitrile moiety, were identified.
A novel series of PAI-1 inhibitors containing an oxadiazolidinedione moiety were identified by high through-put screening.
Macrocyclic compounds bearing a 2-amino-6-arylpyrimidine moiety were identified as potent heat shock protein 90 (Hsp90) inhibitors by modification of 2-amino-6-aryltriazine derivative (CH5015765).
Through extensive SAR studies, analogs bearing free amino groups and alternatives to the parent (S -α-methyl benzyl moiety were identified.
Using an UHPLC-Q-TOF-MS/MS fingerprinting method based on the in-source collision induced dissociation (ISCID) approach, a total of 19 different metabolites with a cinnamic acid core moiety were identified.
Using the described UHPLC-Q-TOF-MS/MS fingerprinting method, based on the ISCID approach, a total of 19 different metabolites with a cinnamic acid core moiety were identified.
Similar(51)
Until that specific moiety is identified, the effect of the avidin-targeting moiety on the microparticle cannot be evaluated.
The 2,6-diaminopyridine moiety was identified as a key component to inhibit Aβ aggregation.
Moreover, an early step catalyzed by a PKS complex leading to a lactone moiety, was identified in the biosynthesis of the meroterpenoid pyripyropene (Itoh 2010).
A 4-subsituted benzoic acid moiety was identified as an advantageous replacement for the 3′3′-dimethylsuccinate moiety present in previously disclosed MIs that illuminates new aspects of the topography of the pharmacophore.
The aglycone moiety was identified as β-sitosterol from its H and APT spectra.
More suggestions(15)
consortium were identified
fraction were identified
proportion were identified
stretch were identified
section were identified
substance were identified
component were identified
moiety were found
moiety were located
moiety were investigated
moiety were generated
moiety was identified
moiety were enhanced
moiety were determined
moiety were described
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