Exact(2)
The isoxazole moiety was inserted in the vicinity of the Zn2+-binding group in order to check its participation in the coordinating process.
To further increase the hydrophilicity of this compound, an additional Ala SO3H) moiety was inserted into the spacer, and this compound (termed F-BAY-86-4367) subnanomolarnomolar GRPR binding affinity, behaving as an antagonist.
Similar(58)
When only FITC-labeled MexA bearing a palmitoyl moiety is inserted into the sponge phase, FRAPP measurements give a single diffusion coefficient, DMexA, whatever the distance dW (Figure 4).
Planar poly methacrylic acid) (PMAA) brushes are synthesized using the "grafting from" free-radical polymerization scheme followed by exposure to a solution of photosensitive surfactants consisting of positively-charged head groups and hydrophobic tails into which azobenzene moieties are inserted.
The 1, N-ϵdG adduct was inserted into the duplex; however, the etheno moiety oriented toward the minor groove.
In the present paper, we have designed and synthesized several T140 analogues, in which an (E -alkene dipE -alkeneostere was insertedipeptidee type isosterern moiety, as a bridging study to develop nonpeptidic CXCR4 inhibitors.
As expected, in several clones, a stop codon was inserted, resulting in truncated peptides; however, all of these truncated peptides contained the protein kinase A substrate moiety.
A Foley catheter was inserted.
Then the laparoscope was inserted.
A peripheral IV was inserted.
A ventriculoperitoneal shunt was inserted.
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