Sentence examples for moiety that binds from inspiring English sources

Furthermore Poelstra et al. have used proteins substituted with a sugar moiety that binds the mannose-6-phosphate-IGFII receptor [ 157].

PNA was a targeting moiety that binds to β-d-galactosyl- 1-3 -N-acetyl-d-galactosamine, which is the terminal sugar of the Thomsen–Friedenreich antigen that is specifically expressed on the mucosal side of colorectal cancer cells.

PNA is a targeting moiety that binds to β-d-galactosyl(1 3 -N-acetyl-d-galactosamine, which is the terminal sugar of the Thomsen-Friedenreich antigen that is specifically expressed on the mucosal side of colorectal cancer cells.

PNA is a targeting moiety that binds to β-d-galactosyl- 1-3 -N-acetyl-d-galactosamine (Gal-β-d-galactosyl- 1-3 -N-acetyl-d-galactosamine the Thomsen–Friedenreich antigen that is specifically expressed on the mucosal side of colorectal cancer cells; it is anchored on the nanosphere surface via a poly(methacrylic) acid (PMAA) linker.

In contrast, the proximal Ub moiety that binds to the enzymatic sitesite contributes the Lys to the isopeptide bond.

Etanercept is a soluble TNF-α type II receptor linked to an IgG1-Fc moiety that binds to and inactivates TNF-α [ 33].

Thus, in the context of the common structure-based pharmacophore, this was translated into a larger radius for the hydrophobic feature (i.e., 3.0 Å) than for the acceptor and donor radii (i.e., 1.5 Å), as a consequence of the huge structural variability found for the inhibitor moieties that bound to the narrow hydrophobic pocket located between the two hIKK-2 lobes (see Figure 2A).

Importantly the possibility that GH 18 proteins mediate their biologic effects via a ligand-receptor paradigm has not been addressed, and moieties that bind to and signal in response to any of these regulators have not been defined.

These alleles are defined by their ability to bind glucose or rhamnose at either position 2″ or 6″ to the glucose moiety that is bound to the 3-position of flavonols.

They sense NO by means of a heme moiety that is bound to their N-terminal extensions.

For analgesic design it suggests further possibilities: design of a moiety that can bind to the Nav1.7 sodium pore; and discovery, and then inhibition, of the chaperone protein that correctly folds Nav1.7 prior to its trafficking to the membrane.