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The main cause of STZ-induced β-cell death is alkylation of DNA by the nitrosourea moiety of this compound.
The bioactivity of a BoNT-A molecule is, however, lost upon the introduction of an iodine atom into the tyrosine moiety of this sensitive molecule.
The composition of the peptide moiety of this potion, or sialome (from the Greek sialo = saliva), can be deducted in part by proper interpretation of the blood feeder' sialotranscriptome.
It is concluded that discovery of (2R,4R -adenine analogue 4c as potent anti-HBV agent suggested that the sugar moiety of this series can be regarded as a novel template for the development of new anti-HBV agent and oxygen atom can be acted as a bioisostere of C–OH.
For example, enzymes called ADP-ribosyltransferases add the ADP-ribose moiety of this molecule to proteins, in a posttranslational modification called ADP-ribosylation.
In wild-type cells, the alkaline phosphatase moiety of this hybrid is translocated to the periplasmic space where it exhibits relatively high alkaline phosphatase activity [16].
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Interestingly, the human structure most closely resembles the inhibitor-bound structure, suggesting that binding of the phosphate moiety of the substrate may trigger this conformational change.
However, in the crystal structure of fully reduced Rs aa3, there is a bridging water molecule that forms H-bonds with both the phenolic OH and the hydroxyethyl moiety of the high-spin heme; this bridging water is not present in the G232V mutant.
In this position the aldehyde moiety of the retinal is located in the polar cavity described above.
Even if this solubility enhancer is regarded as a pure surfactant in the literature, it appears that the oil moieties of this macrogolglyceride mixture significantly influence its properties.
The major moieties of this oligomeric drug are Sb v ligand complexes that are zwitterionic in solution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com