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Heminephrectomy remains an excellent option for a poorly functioning moiety in a duplicated collecting system.
The tungsten-oxo moiety in a simple monomeric tungstate, TBA2[WO4] (I, TBA = tetra-n-butylammonium), showed bifunctional activation of both CO2 and 1,2-phenylenediamine (1a).
This is achieved by posttranslational modifications, including the addition of a farnesyl isoprenoid moiety in a reaction catalyzed by the enzyme protein farnesyltransferase (FTase).
A new hybrid template has been designed by integrating the structural features of nimesulide and the 1,2,3-triazole moiety in a single molecular entity at the same time eliminating the problematic nitro group of nimesulide.
Crystallographic structural information was used in the design and synthesis of a number of bioisosteric derivatives to replace the amide moiety in a lead series of p38α inhibitors which showed general hydrolytic instability in human liver preparations.
The peptide sequence was enriched with an additional cysteine so it can be involved as a reactive moiety in a certain orientation- and sequence-specific coupling of the CPP to the PEG shell of the NPs.
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From the docking analysis, experimental inhibitory potency relationship of compounds 1 7 exhibited the fundamental role of α,β-unsaturated carbonyl moiety in ring "A".
In the moiety system all people, things, and phenomena are assigned to a moiety in an all-encompassing classificatory system.
For this we synthesized a biotinylated analogue of QL47, QL47B, where we installed the biotin moiety in an analogous position to where BODIPY has previously been appended to Ibrutinib.
They found that oxidation of Trp occurs at the C2 position of the pyrrole ring followed by the hydroxylation at the C7 position of the indole benzene moiety in an irreversible pH-dependent process.
Fig. 5 The preferential conformation-based, ball-stick models of epicatechin (a) and luteolin-7-O-β-D-glucoside (b) Fig. 6 The proposed Fe2+-binding reactions with a catechol moiety in epicatechin (a) and with catechol and hydroxyl-keto moieties in luteolin-7-O-β-D-glucoside (b).
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