The QM moiety has been proposed to be a biosynthetic intermediate in the assembly of some natural products55,56,57.
The sulfamide moiety has been utilized to design novel HDAC inhibitors.
Redox active ferrocene moiety has been covalently attached to the terminal azido groups in the SAM using "click" chemistry.
This approach, which exalts the anti-cancer properties of the organic moiety, has been successfully used to design ferrocifens.
Introduction of an acyl group at the NH2 of the thiourea moiety has been found to enhance inhibitory activity.
A nitronyl nitroxide bearing a uracil moiety has been shown to exist in at least three different forms in crystals.
The 4- 3-piperidinopropoxy phenyl pharmacophore moiety has been linked to amitriptyline, maprotiline, chlorpromazine, chlorprothixene, fluphenazine, and clozapine.
A reactive amphiphile, SA1, which comprises a mercaptodecyl oleophilic tail and a β-alanine oleophobic moiety, has been introduced to serve as the building block for supramolecular filler.
We synthesised a series of analogues of glutathione (l-γ-Glu-l-Leu-X) where the glycine moiety has been substituted for other amino acids.
A small series of C-cinnamoyl glycosides incorporating the phenol moiety has been prepared by reaction of glycosyl ketones with the appropriate benzaldehydes.
A new, acyclic NAD-analog, acycloNAD+ has been synthesized where the nicotinamide ribosyl moiety has been replaced by the nicotinamide 2-hydroxyethoxy methyll moiety.
