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Protein kinases catalyze the transfer of a phosphate moiety from a phosphate donor to the substrate molecule, thus playing critical roles in cell signaling and metabolism.
The current work is an attempt to co-deliver topotecan (hydrophilic moiety) and thymoquinone (lipophilic moiety) from a nanomatrix eliciting a suitable release profile.
Stimulus-induced heat generation can also be utilized to control dissociation of a therapeutic moiety from a thermoresponsive carrier that undergoes reversible volume or sol-gel phase transition within a desired range of 37°C to 45°C [14 16].
The first step was a cleavage of a glycan moiety from a protein or a peptide backbone either enzymatically or chemically.
In general, this application relies on the target-induced release of a β-fructofuranosidase moiety from a functional DNA-enzyme conjugate.
This species forms via the transfer of a [Ph2P]+ moiety from a second equivalent of 36f + to the reactive intermediate 60f +.
Similar(48)
Glycosyltransferases (GTs) are ubiquitous enzymes that catalyse the transfer of a sugar moiety from an activated sugar donor to saccharide or non-saccharide acceptors, forming glycosidic bonds.
Glycosyltransferases are a ubiquitous group of enzymes that catalyse the transfer of a sugar moiety from an activated sugar donor onto saccharide or non-saccharide acceptors.
The elimination of the sugar moiety from an Amadori product may also result in an incorrect identification of the modification site.
Transfer of the P-pant moiety from coenzyme A to a serine residue is catalyzed by 4′-phosphopantetheinyl transferase (PPTase).
Ppant transferases catalyze the transfer of the Ppant moiety from coenzyme A to a holo-acyl, -aryl, or -peptidyl carrier protein required for the biosynthesis of fatty acids, polyketides or nonribosomal peptides.
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