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time scale resulted in separate signals for the amino and imino moiety due to preference for the E-anti configuration of the amidine group.
The alteration of geometrical parameters of the cation, as compared to 4- pyridinium-1-yl -phenolate molecule, is observed only in the phenolate moiety due to the protonation of the oxygen atom.
Also, pH levels higher than 8 should be avoided because of quinone formation of the catechol moiety due to oxidation.
Recently, Apt based on single-stranded nucleic acid molecules have been developed as a targeting moiety due to their high affinity and selectivity for a variety of chemical and biological molecules[13].
A partial loss of the functional bisphosphonate moiety due to stabilizing the 177Lu III) complex might reduce the binding potential of the bisphosphonate group to the bone and thus reduces the affinity of the [177Lu]NO2APBP compound to the target tissue in contrast to the 68Ga III) complex.
The nucleotide base binding cavity in GpgS is similar in size to the one in MgS, but the position of residue Ser81 in GpgS (Tyr87 in MgS), would prevent binding of the NH2 at position 2 of the guanine moiety due to steric hindrance (Fig. 5a).
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The thermoresponsive behavior of the resulted phe-g-PHPA polymers can be tuned by adjusting the graft copolymer composition and partial removal of pendant aromatic moieties due to the hydrolytic degradation, which can be used for controlled drug release.
The NHC fractions are enriched in aromatic moieties due to the removal of carbohydrates and proteins.
The signals observed in 3.3 4.2 ppm correspond to the fingerprint region of sugar moieties due to the protons attached to C2 C6 and poorly resolved because of the overlapping chemical shifts.
This method is also favorable because complexation depends upon the configuration of the fatty acid moieties due to the presence of multiple double bonds, rather than pure physical properties such as melting point or solubility [10].
This method is preferred by many researchers because complexation depends upon configuration of the FAs moieties due to the presence of multiple double bonds, rather than pure physical properties such as melting point or solubility [5, 6].
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