Sentence examples for moiety did not from inspiring English sources

Exact(21)

Whereas modifying the aminoethyl moiety did not significantly change TRPV6 inhibition, substitution of the phenyl rings of 2-APB did.

In previous structure activity relationship studies, we have demonstrated that certain modifications around the fucoside moiety did not cause significant cytotoxicity loss.

Biological tests revealed that repeating unit 3, lacking the lipid moiety, did not stimulate a pro-inflammatory response in human monocytes (hMNCs).

However, the 3R*-methyl compound 7, bearing a 5-iminoethyl moiety, did not inhibit any of the NOS isozymes, although l-N-iminoethylornithine (l-NIO) potently inhibited all three.

For such moieties (haloanions), the cdkrecharge marks all halogens as neutral, puts all negative charge on a single "central" atom, and, if the total charge of the processed moiety did not change, replaces its representation by a new SMILES sub-string generated from a moiety with redistributed charges; if any of the mentioned checks fails, the moiety is left unaltered.

The C-terminal GFP moiety did not affect the expression of the proteins nor their activity.

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Similar(39)

Structure activity relationships (SARs) and docking studies indicated that replacement of the aqueous solubility 4- dimethylamino but-2-enamide group by cinnamamide moiety didn't decrease the antitumor activity.

Introduction of methyls to the ribose moiety does not lead to inhibition of TBEV reproduction.

The chemical nature of a meta-substituent on the 5-APT pendant phenyl moiety does not significantly affect H1 affinity.

Our results indicate that, regardless of the genomic context, the histidine moiety does not become incorporated in proteins via ribosomal translation, and that disruption of the TLS in either viral RNA does not perturb the viral translation patterns.

Moreover the absence of the 1,2-dithiolane moiety does not completely abolish antioxidant effects thus demonstrating that these compounds are distinct new chemical entities and not merely lipoic acid prodrugs.

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