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In contrast, enzymatic hydrolysis can hydrolyze specific sugar moieties with high productivity and no by-products.
Further investigation of the quality of these polymers could lead to the identification of single carbohydrate or protein moieties with high gluing and stabilizing capability.
With the aim to pick out novel and potent PDK1 inhibitors, herein we report the design and synthesis of a new class of molecules obtained by merging the 2-oxo-indole nucleus with the 2-oxo-pyridonyl fragment, two moieties with high affinity for the PDK1 hinge region and its DFG-out binding site, respectively.
The grafted MDMH moieties with high reaction activity and free chlorine could play as sacrificial pendant groups when membranes suffer from chlorine attacks, and the chlorination products N-halamines with strong antimicrobial function could sterilize microorganisms on membrane surfaces and then regenerate to MDMH.
Lectins are carbohydrate-binding proteins, which recognize and bind to specific sugar moieties with high specificity [34].
In this polymer, the boronic acid moiety binds compounds containing vicinal diol moieties with high affinity through reversible esterification.
Similar(54)
The formation of in situ generated twin monomer moieties with higher functionalities f = n 2 (n > 2, n is the assumed average degree of polymerization of the linear chain fragments resulting intermediately from APSI and BADGE), compared to the primary reactant APSI (f = 2, n = 1), triggers the polysiloxane network formation.
Third, a folate-linker moiety with high affinity for FRα was synthesized and conjugated via an orthogonally protected lysine on the peptide sequence.
Caffeine has been used as a scaffold for the design of inhibitors of monoamine oxidase (MAO) A and B. Substitution at the C8 position with a variety of moieties yields structures with high MAO inhibition potencies.
Ligands with a hydantoin moiety bind with higher affinity than those with other nucleobase-like entities.
Ligand exchange typically employs a functional moiety with a high affinity for binding to the surface of quantum dots (B), a spacer group (such as an alkyl or aryl chain, S), and a functional group or chain that possesses the chemical property of interest (F).
Related(20)
fractions with high
sections with high
periods with high
spouses with high
sizes with high
pieces with high
stretches with high
portions with high
clusters with high
sides with high
ends with high
groups with high
groupings with high
segments with high
moieties with chiral
moieties with hydroxyl
moieties with secondary
moieties with hydrophobic
moieties with sulfur-containing
moieties with organic
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