Sentence examples for moieties were identified from inspiring English sources

A total of 12 such structural moieties were identified, and they can be used as human hepatotoxicity structural alerts to filter compound libraries and prioritize/profile drug candidates.

The absolute configurations of the sugar moieties were identified as d-glucose (t R = 19.0 min), d-galactose (t R = 23.0 min), d-xylose (t R = 18.3 min), and l-rhamnose (t R = 15.4 min), respectively.

The XPS and DRIFT measurements revealed that three various types of N-containing species (primary amino groups, residual formamide groups and protonated amino moieties) were identified on the surface of the PVAm/SiO2 hybrid materials.

Once the optimal amide moieties were identified in 19, further analogs 22 were accessed by acylation of 16b with picolinic acids under HATU conditions to deliver 20.

Antibodies to RNA moieties were identified by protein A-sepharose-assisted immunoprecipitation from patient sera incubated with Jurkat cell lysate and analysis by silver staining of 7% polyacrylamide/urea gels.

Among the twelve proposed extensions in different combinations, compound 14 (consists of para-fluoro phenyl group as both P1 and P1′ moieties) was identified as a lead with improved binding profile, binding affinity against the MDR protease and favorable predicted pharmacological properties comparable to those of LPV.

Analysis of the actual surface chemistry rather than presumption of its composition using the monomer identity is essential to ensure the controlling moieties are identified since both surface segregation of certain monomers and contamination can occur in spots.

Several compounds with single-digit or even sub-nanomolar potency, suitable for further elaboration of the nitrile moiety, were identified.

A novel series of PAI-1 inhibitors containing an oxadiazolidinedione moiety were identified by high through-put screening.

Macrocyclic compounds bearing a 2-amino-6-arylpyrimidine moiety were identified as potent heat shock protein 90 (Hsp90) inhibitors by modification of 2-amino-6-aryltriazine derivative (CH5015765).

Through extensive SAR studies, analogs bearing free amino groups and alternatives to the parent (S -α-methyl benzyl moiety were identified.