Your English writing platform
Discover LudwigExact(1)
Among the twelve proposed extensions in different combinations, compound 14 (consists of para-fluoro phenyl group as both P1 and P1′ moieties) was identified as a lead with improved binding profile, binding affinity against the MDR protease and favorable predicted pharmacological properties comparable to those of LPV.
Similar(59)
A total of 12 such structural moieties were identified, and they can be used as human hepatotoxicity structural alerts to filter compound libraries and prioritize/profile drug candidates.
The absolute configurations of the sugar moieties were identified as d-glucose (t R = 19.0 min), d-galactose (t R = 23.0 min), d-xylose (t R = 18.3 min), and l-rhamnose (t R = 15.4 min), respectively.
The XPS and DRIFT measurements revealed that three various types of N-containing species (primary amino groups, residual formamide groups and protonated amino moieties) were identified on the surface of the PVAm/SiO2 hybrid materials.
Once the optimal amide moieties were identified in 19, further analogs 22 were accessed by acylation of 16b with picolinic acids under HATU conditions to deliver 20.
Analysis of the actual surface chemistry rather than presumption of its composition using the monomer identity is essential to ensure the controlling moieties are identified since both surface segregation of certain monomers and contamination can occur in spots.
Antibodies to RNA moieties were identified by protein A-sepharose-assisted immunoprecipitation from patient sera incubated with Jurkat cell lysate and analysis by silver staining of 7% polyacrylamide/urea gels.
The 2,6-diaminopyridine moiety was identified as a key component to inhibit Aβ aggregation.
Moreover, an early step catalyzed by a PKS complex leading to a lactone moiety, was identified in the biosynthesis of the meroterpenoid pyripyropene (Itoh 2010).
A 4-subsituted benzoic acid moiety was identified as an advantageous replacement for the 3′3′-dimethylsuccinate moiety present in previously disclosed MIs that illuminates new aspects of the topography of the pharmacophore.
The aglycone moiety was identified as β-sitosterol from its H and APT spectra.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com