Sentence examples for moieties necessary for from inspiring English sources

Fragments contained both 5′ phosphate and 3′ hydroxyl moieties necessary for ligation.

Structure activity relationship studies using novel analogues of 1 3 revealed that two phenylsulfonic acid moieties were necessary for activity and that the carbon carbon double bond of the stilbene sub-series was the optimum spacer connecting these groups.

While the farnesyl and carboxy-methyl moieties are necessary for lamin B functions their persistence in progerin and FC-lamin A causes multiple abnormalities in nuclear structure and function [ 11, 16, 20, 23, 27, 31, 32].

The discrepancy between these results and an earlier report showing that chains of more than two SUMO moieties were necessary for efficient ubiquitylation by RNF4 in vitro [ 24] can be resolved by considering the protein concentrations.

As a similar effect, although not as pronounced, was seen when increasing the rigidity of the main chain by replacing the central thiophene with selenophene, it could be concluded that conformational freedom along the conjugated backbone in combination with end carboxyl moieties is necessary for achieving superior spectral separation of the two pathological hallmarks observed in AD.

The fact that the isolated HOXA9 moiety (HOXA9ΔN) had no effect on differentiation shows that the NUP98 moiety is necessary for disruption of human hematopoietic differentiation.

This observation suggests the cross-linking might follow [4 + 2] cycloaddition reaction between diene of biphenyl moiety and dienophile of PFCP ring, and thus the presence of biphenyl (diene) moiety is necessary for network formation.

An unsaturated C-8 C-9 moiety was neC-8 C-9 for RTK inhibitory activity.

Structure activity relationships (SARs) and docking studies indicated that the chromone moiety is necessary for the potent antitumor activity and cytotoxicity of these compounds.

Kinetic (Km and Vmax) and inhibition constants (Ki) were measured and reveal that almost the entire γ-glutamyl moiety is necessary for recognition in the binding site of the donor substrate.

This may be due to the simplicity of its structure such that AD28 may not have key moieties or interactions necessary for subsequent findings observed with Gleevec and AD95.