The design, synthesis, biological activity, and the binding modes of non-covalent thrombin inhibitors featuring P1-4,5,6,7-tetrahydroindazole, 5,6,7,8-tetrahydroquinazoline, and 4,5,6,7-tetrahydrobenzothiazole 4,5,6,7-tetrahydrobenzothiazole
The synthesis and in vitro characterization of novel RXR-selective ligands possessing various substituted 1-benzofuran or 1-benzothiophene moieties are described.
The synthesis of well-defined heteroarm star-branched polymers having poly tBMA) arms by the coupling reactions of living anionic polymers of tert-butyl methacrylate (tBMA) with chain-functionalized polymers with a definite number of benzyl halide moieties was described.
Their structures are versatile and many different hydrophilic and hydrophobic moieties are described in literature (Hausmann and Syldatk 2014; Kügler et al. 2015).
The cytokine field is constantly growing as novel moieties are described.
Tailor made synthesis of the azoaromatics, HL1 HL2 [HL = 2- arylamino phenylazopyridine] containing ionophoric crown moiety is described.
