Sentence examples for moieties in order from inspiring English sources
The original arylazolylthioacetanilide platform was replaced with different imidazopyridinyl- thioacetanilide scaffolds to yield the optimal pharmacophore moieties in order to generate novel NNRTIs with desirable potency.
Indeed, dendrimers can possess many terminal functional groups that can be chemically linked to other moieties in order to adjust their surface properties for applications such as biomimetic nano-devices.
In this article, the original thiazole platform was replaced with pyrazole scaffold to yield the optimal pharmacophore moieties in order to generate novel non-nucleoside HBV inhibitors with desirable potency.
It would therefore be interesting to evaluate the type of interaction between the moieties in order to design such surfactant aided immobilized system for better inhibitory action of BHA which could prove valuable to pharmaceutical or cosmeceutical industries.
The substituent in position 2 of the quinoline nucleus of NK1 receptor ligands 5 has been constrained into different five-membered heterocyclic moieties in order to obtain information on the binding site pocket interacting with this apparently critical portion of ligands 5.
With a view towards in vivo targeting, another critical consideration was the affinity between the linking moieties in order to minimize the potential for dissociation of the targeted Ad/scFv complex.
A seven atom spacer group was incorporated between the bulky calixarene core and the acrylate moiety in order to minimize steric interactions which proved to impede the polymerization.
Drug has been covalently linked to the nanoparticle through an ester bond with the 20-hydroxy moiety, in order to stabilize its lactone ring and to avoid unspecific release of the drug.
As a part of our research projects to synthesize new bioactive compounds [26 34], we intended in this research to synthesize a new series of thiazoles carrying 1,3,4-thiadiazole moiety in order to study their anticancer activity against liver carcinoma cell line (HepG2).
In this study, a mixture of cationic DNA intercalator, benzo[b]quinolizinium-crown ether, and DNA was explored as a AgNP formation moiety in order to avoid undesired degradation as a result of the exposure to high-energy light needed for the AgNP synthesis, as shown in Fig. 3.
The tight fit of the sugar moiety into this pocket would prevent a shift in the position of the mannose moiety, in order to prevent steric hindrance with this carbonyl group.
