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This may be because in the HB-FePc catalyst, the biphenyl linker connecting phthalocyanine moieties does not decompose, which suppresses liberation/sublimation of each component below 600°C.
The observation is rationalized by DFT molecular modeling, which suggests that upon the formation of 1 1 cyclic supramolecular complexes the chiral twist direction of the two porphyrin moieties does not change, while the ZnZn distance increases remarkably.
Thus, the increase in the molar concentration of the Li-sulfonate moieties does not lead to higher conductivities either because the number of "free", i.e. mobile, charge carriers is decreased or because the mobility of the ionic species is drastically reduced due to the lack of segmental motion of the matrix.
SbpA lacking the protein G moieties does not have any affinity for IgG.
In any case, binding to non-cleavable substrate moieties does not seem to be a prerequisite for the hemadsorption-mediated enhancement of the catalytic efficiency, as the enhancement effect was observed in the case of mono-specific sialylglycopolymers 3SL-PAA and 6SLN-PAA (Fig. 3b) that do not carry non-cleavable sialic acid residues.
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This indicates that such moieties do not undergo phase transition or magnetic ordering, supporting the view that the active sites are localized on isolated iron atoms.
These findings suggest that "undesirable" moieties do not pose a major hindrance during clinical trials, the most expensive phase of drug development.
The electrochemical characterization showed that the presence of the hydrophobic moieties did not affect the metal nanoparticle synthesis protocol, attesting to the possibility of obtaining a bifunctional material containing both the metallic nanoparticles and the aromatic moieties employed for enzyme orientation.
Figure 4A shows that when labeled oxLDL-IC and oxLDL were administered simultaneously their lipid moieties did not appear to co-localize 5 h post treatment.
Similarly, the deglycosylated rhinocerase was inhibited by the same concentration of PMSF as native rhinocerase indicating that the glycosylated moieties do not affect the binding of PMSF.
Conversely, in the presence of the NH1-Val18 and CO1-Phe20 hydrogen bonds, the indole and naphthoquinone moieties do not act as "clamp" but rather interact with the Val18 and Phe19 side chains, respectively (Figure 7D).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com