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Indeed, a number of substrates decorated with various additional sugar moieties are utilized by these highly selective hexosaminidases.
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Functional polyphosphazene cyclomatrix microspheres (PMS) containing glucose and dodecyl moieties were utilized for physical adsorption of lipase.
In these dyes, triphenylamine moiety was utilized as electron donor and cyanoacetic acid acts as an electron acceptor.
As lactate is a cerebral metabolite, it is important to evaluate if this moiety is utilized in an oxidative manner by the brain cells.
Thus, a longer alkyl chain between the thiol group and the TEG moiety was utilized (C11TEG, Fig. 1) in this study to achieve a higher density SAM, relative to C3TEG to inhibit serum adsorption.
Both melibiose and lactose are disaccharides composed of galactose and glucose moieties, and both are utilized only after internalization through their respective transporters; lactose via a lactose-specific PTS and melibiose through the Msm ABC transporter [16], [17].
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Many clinical cancer biomarkers correspond to glycosylated molecules and the alterations in their glycan moieties can be utilized as a target to improve existing cancer biomarkers.
The sulfamide moiety has been utilized to design novel HDAC inhibitors.
Moreover, we have shown that TPE-based fluorescent oligosaccharide probe bearing 6′-sialyllactose moiety can be utilized as a "turn-on" fluorescent sensor for detection of influenza virus.
For instance, a single targeting moiety (RGD) was utilized to target both BBTB and tumor cells.
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