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Third, two new synthetic methods for preparing chiral helical poly phenylacetylene)s without the coexistence of any other chiral moieties are presented.
This suggests that the cyclohexane ring contributes to inhibitory activity by either hydrophobic interactions, or by controlling the orientation by which the other moieties are presented to the protein.
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In this chapter, the latest advances in supramolecular biomaterials research based on two different hydrogen-bonding units, i.e., the ureidopyrimidinone (UPy) and benzene-1,3,5-tricarboxamide (BTA) moiety, are presented.
The synthesis, liquid crystalline and optical properties of copper (II), oxovanadium (IV) and gadolinium (III) complexes derived from polar Schiff's bases viz., N- 4-n-hexadecyloxysalicylidene -4′-substituted aN- 4-n-hexadecyloxysalicylidene -4′-substitutedueN- 4-n-hexadecyloxysalicylidene -4′-substitutedeN- 4-n-hexadecyloxysalicylidene -4′-substituted
For example, formulations made from enhancer mixtures are most potent when participating moieties are present in nearly equal fractions.
N-alkylated benzyl amines are particularly important targets, as these moieties are present in a variety of drug molecules, for example, a glycine transporter type 1 inhibitor, which has shown potential in the treatment of schizophrenia29 (Fig. 6b). Figure 6: Synthesis of pharmaceutically active molecules.
Here, we test this proposal by showing that a genetically engineered form of cbb3 from Vibrio cholerae (CcoNOQPX) that lacks the hydrophilic domain of CcoP, where the two heme c moieties are present, is fully assembled and stable.
Results obtained with the VS-2 catalyst showed that vanadium oxide moieties are present within the zeolite framework as a 4-fold tetrahedrally coordinated vanadium oxide species having a terminal oxovanadium group (VO).
The catalytic behaviour observed (activity and selectivity) showed that both Ru and Rh systems are less active in scCO2 than in THF, preventing the hydrogenation of the aromatic group when electron-donor groups (like ether moieties) are present on the substrate.
Glycosylation moieties are present in SSTR5 [212].
If reactive DHAA moieties are present in the cell-surface extract, the resulting DTT adducts increase the mass of the exported metabolite by multiples of 154.0 Da.
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