Sentence examples for moieties are important from inspiring English sources
The 1,3,4-oxadiazoles and diclofenac moieties are important because of their versatile biological actions.
β-Carboline moieties are important structural subunits which occur as components of many biologically interesting molecules for antitumor activity.
If carboxylate moieties are important for TMEM16A-calcium interaction, these mutations may partially preserve TMEM16A-CaCC calcium sensitivity even if the change in side chain length alters the position of the carboxylate group.
Structure activity relationship analysis of these analogues demonstrated that the integrity of α,β-unsaturated carbonyl and acetyl moieties were important in the retention of glucose uptake stimulatory effect.
109c Beginning at the N-terminal (R1) position of compounds related to 35, it was found that increasing lipophilicity improved potency and that the stereochemistry around methyl-substituted cyclohexyl moieties was important (36).
The 2′ and 4′ hydroxyl groups of the receiving Gal moiety are important in binding.
The presence of lipophobic groups, such as quinoline nucleus, cyclopropyl and substituted thiophenyl groups as well as a lactone moiety, is important for binding to the active sites.
Arixanthomycins B (2) and C (3) are significantly less active in these assays, suggesting that the sugar moiety is important for the antiproliferative activity of 1.
Based on molecular modeling studies, performed using the crystal structure of Haemophilus haemolyticus cytosine-5 DNA methyltransferase (MHhaI C5 DNMT), which suggested that the quinoline and the aminopyridimine moieties of SGI-1027 are important for interaction with the substrates and protein, we designed and synthesized 25 derivatives.
However, it is still unclear how KS15 impairs the feedback actions of the CRYs and which chemical moieties are functionally important for its actions.
Pyrazoles are important moieties as building blocks for many heterocyclic products and act as abinucleophile [2] with abroad spectrum of remarkable biological activities.
